Isotopically Labeled Compounds
Medchemexpress LLC Stearic acid-d5 | 211443-83-3 | ≥99% | 100 MG
Stearic acid-d5 is a deuterium labeled stearic acid, a long-chain dietary saturated fatty acid found in various animal and vegetable fats and oils. It is commonly used as an internal standard for the quantification of stearic acid by GC- or LC-MS. Deuterium labeling incorporates stable heavy isotopes into molecules, which can serve as tracers for quantitation during drug development and may impact pharmacokinetic and metabolic profiles of drugs.
- Used as an internal standard for quantification.
- Deuterium labeled.
- Functions as a tracer for quantitation during drug development.
- May affect pharmacokinetic and metabolic profiles.
- Long-chain saturated fatty acid.
Medchemexpress LLC Lactic acid-d4 sodium | 344299-52-1 | 99.0% | 1 MG
Lactic acid-d4 sodium | 344299-52-1 | 99.0% | 1 MG
Cayman Chemical EtIfoxIn-13C-d3 500ug
An internal standard for the quantification of etifoxine by GC- or LC-MS
Medchemexpress LLC 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7 | 1392208-04-6 | 99.6% | 1 MG
(Rac)-Ropivacaine-d7 is a stable isotope-labeled compound, identified as 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-propyl-d7. It appears as a white to off-white solid with an isotopic enrichment of 99.11%. This product is intended for research use only and should be handled by qualified personnel in appropriately equipped facilities.
- High purity of 99.6% (HPLC)
- Stable under recommended storage conditions
- Ideal for laboratory chemical applications and substance manufacturing
- For research use only
Medchemexpress LLC Mebeverine acid-d5, hydrochloride | 475203-77-1 | 99.0% | 1 MG
Mebeverine acid-d5 hydrochloride is a deuterium labeled form of Mebeverine acid hydrochloride, a secondary metabolite of the intestinal antispasmodic agent Mebeverine. It is formed by the body's hydrolysis of Mebeverine, acting as a key circulating metabolite and an important marker for oral Mebeverine. This compound is intended for research use only, leveraging stable heavy isotopes for quantitation in drug development.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Cambridge Isotope Laboratories ALPHA-KETOISOCAPROIC ACID0.1GM
ALPHA-KETOISOCAPROIC ACID, SODIUM SALT (ISOPROPYL-D7, 98%) 0.1gm
Medchemexpress LLC Benzyl benzoate-d12 | 352431-26-6 | 99.9% | 5 MG
Benzyl benzoate-d12 is a deuterium-labeled form of Benzyl benzoate, also known as Benzoic acid benzyl ester-d12. It serves as a fragrance ingredient in cosmetic products and is utilized in research for Scabies and Demodex-associated inflammatory skin conditions. It is for research use only and not sold to patients. Deuteration, the incorporation of stable heavy isotopes of hydrogen, carbon, and other elements, is a key feature, offering potential benefits by affecting the pharmacokinetic and metabolic profiles of drugs during development.
- Used as a fragrance ingredient in cosmetic products.
- Utilized in research for Scabies and Demodex-associated inflammatory skin conditions.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuteration affects the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Ropivacaine-d7 | 684647-62-9 | 99.7% | 5 MG
Ropivacaine-d7 is deuterium labeled Ropivacaine. Ropivacaine is a potent sodium channel blocker, which blocks impulse conduction by reversibly inhibiting sodium ion influx in nerve fibers. It is also an inhibitor of K2P (two-pore domain potassium channel) TREK-1 with an IC50 of 402.7 μM in COS-7 cell's membrane. Ropivacaine is used for the research of neuropathic pain management. It can be used as a tracer or an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled Ropivacaine
- Potent sodium channel blocker
- Inhibits impulse conduction by reversibly inhibiting sodium ion influx
- Inhibitor of K2P (two-pore domain potassium channel) TREK-1
- Used for research in neuropathic pain management
- Can be used as a tracer or internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Related to isotope-labeled compounds
- Useful for therapeutic drug monitoring
SIGMA ALDRICH FINE CHEMICALS BIOSCIENCES PREGNENOLONE 20 21 13C2 16 16
NC3827175 PREGNENOLONE 20 21 13C2 16 16
Medchemexpress LLC Deruxtecan-d5 | 1599440-13-7 | 98.4% | 1039.08 | 1 MG
Deruxtecan-d5 is a deuterium-labeled version of Deruxtecan. It is an ADC (Antibody-Drug Conjugate) drug-linker conjugate composed of a DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Benzyl alcohol-d7 | 71258-23-6 | 99.56% | 50 MG
Benzyl alcohol-d7 is the deuterium labeled Benzyl alcohol, an aromatic alcohol that is a colorless liquid with a mild pleasant aromatic odor. It can be used as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Used as a tracer
- Functions as an internal standard for quantitative analysis (NMR, GC-MS, LC-MS)
- Store pure form at -20°C for 3 years or 4°C for 2 years
- Store in solvent at -80°C for 6 months or -20°C for 1 month
- Keep container tightly sealed in a cool, well-ventilated area
- Keep away from direct sunlight and sources of ignition
- Stable under recommended storage conditions
Medchemexpress LLC Tetrabenazine-d6 | 1392826-25-3 | 98.2% | 5 MG
Tetrabenazine-d6 (Deutetrabenazine) is a deuterium-labeled Tetrabenazine, which is the first deuterium approved worldwide for the research of Huntington's disease, or other hyperkinetic movement disorders.
- Extend the half-life in vivo.
- Improve oral bioavailability.
- Improve metabolic characteristics.
- Improve drug safety.
- Preserve the therapeutic properties.
Medchemexpress LLC Pimobendan-d3 | 74150-27-9 | 99.4% | 5 MG
Pimobendan-d3 (UD-CG115-d3) is deuterium labeled Pimobendan (HY-B0204), a selective inhibitor of PDE3 with an IC50 of 0.32 μM. It is intended for research use only and not sold to patients. This compound can be used as a tracer and internal standard for quantitative analysis by NMR, GC-MS, or LC-MS. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer and internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuterium labeled for potential impact on pharmacokinetic and metabolic profiles
- Intended for research use only
Medchemexpress LLC Florfenicol-d3 | 2213400-85-0 | 99.9% | 5 MG
Florfenicol-d3 is the deuterium labeled form of Florfenicol, a veterinary antibiotic. It is used for bovine respiratory disease and in aquaculture to control enteric septicemia in catfish. Florfenicol can induce early embryonic death in eggs, with an LC50 of 1.07 μg/g. This product is for research use only.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Stable heavy isotopes have been incorporated into drug molecules for quantitation during drug development.
- Deuteration can affect the pharmacokinetic and metabolic profiles of drugs.
Medchemexpress LLC Diphenhydramine-d5 hydrochloride | 1219795-16-0 | 99.8% | 1 MG
Diphenhydramine-d5 hydrochloride is a deuterium-labeled form of Diphenhydramine hydrochloride. This compound acts as a first-generation histamine H1-receptor antagonist with anticholinergic effects and can cross the ovine blood-brain barrier (BBB). It is intended for research use only.
- Can be used as a tracer
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs
- Stable heavy isotopes are incorporated into drug molecules for quantitation during drug development